Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587402 | 0.94 | FOLH1 (0.53) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL7389852 | 0.89 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL392082 | 0.88 | ALDH1A1 (0.52) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL7434226 | 0.86 | LMNA (0.47) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL10395862 | 0.86 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL10395861 | 0.86 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL391430 | 0.86 | FOLH1 (0.60) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL7434454 | 0.85 | FOLH1 (0.59) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL28002117 | 0.81 | RAB9A (0.54) | ALDH1A1RAB9ANPC1KMT2AMITF | |
| SCHEMBL7431904 | 0.80 | NR1H4 (0.48) | ALDH1A1RAB9ANPC1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |