Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695418 | 0.82 | L3MBTL1 (0.39) | SMN1; SMN2ALDH1A1KMT2AHIF1ALMNA | |
| SCHEMBL8692122 | 0.81 | L3MBTL1 (0.38) | ACHESMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL8695505 | 0.80 | BACE1 (0.40) | SMN1; SMN2ALDH1A1RAB9AKDM4EELANE | |
| SCHEMBL1992937 | 0.80 | KMT2A (0.45) | NLRP3ACHESMN1; SMN2ELANEKMT2A | |
| SCHEMBL8694781 | 0.78 | L3MBTL1 (0.38) | ACHESMN1; SMN2RAB9AELANEKMT2A | |
| SCHEMBL7396550 | 0.77 | ELANE (0.40) | ACHESMN1; SMN2RAB9AKDM4EELANE | |
| SCHEMBL3456935 | 0.76 | RIPK1 (0.43) | SMN1; SMN2RAB9AKDM4EMAOBKMT2A | |
| SCHEMBL6535106 | 0.75 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL6060769 | 0.74 | CA1 (0.41) | NLRP3ACHESMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL7508588 | 0.73 | SMN1; SMN2 (0.43) | ACHESMN1; SMN2ALDH1A1KDM4EELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |