Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GPX4 | P36969 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291683 | 0.85 | SIGMAR1 (0.55) | MEN1KMT2AALDH1A1KDM4ETP53 | |
| SCHEMBL7435696 | 0.82 | NPC1 (0.51) | MEN1KMT2AALDH1A1TP53SIGMAR1 | |
| SCHEMBL7446241 | 0.79 | DRD4 (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7279133 | 0.74 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1TP53MAPT | |
| SCHEMBL7291916 | 0.74 | SIGMAR1 (0.44) | ALDH1A1TP53SIGMAR1OPRM1CHRM2 | |
| SCHEMBL7288766 | 0.72 | TP53 (0.50) | MEN1KMT2AALDH1A1TP53TSHR | |
| SCHEMBL7282050 | 0.71 | HRH1 (0.44) | ALDH1A1KDM4ESIGMAR1OPRM1CHRM2 | |
| SCHEMBL11507051 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1TP53NPC1 | |
| SCHEMBL7274382 | 0.71 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1TP53MAPT | |
| SCHEMBL7440849 | 0.70 | ELANE (0.35) | ALDH1A1KDM4ETSHRCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |