Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432491 | 0.80 | HRH3 (0.47) | HRH3HTR1AGRIN2DGRIN3BADRA1D | |
| SCHEMBL4796352 | 0.80 | HTR1A (0.61) | HTR1ASLC6A4KCNH2ADRA1A | |
| SCHEMBL7983037 | 0.79 | GRIN2B (0.61) | HTR1ASLC6A4GRIN2DGRIN3BADRA1D | |
| SCHEMBL28753859 | 0.79 | HTR1A (0.61) | HTR1ASLC6A4 | |
| SCHEMBL7547846 | 0.79 | HTR1A (0.61) | HTR1ASLC6A4 | |
| SCHEMBL7357631 | 0.78 | HTR1A (0.62) | HTR1ASLC6A4 | |
| SCHEMBL8105223 | 0.78 | HTR1A (0.62) | HTR1ASLC6A4KCNH2ADRA1A | |
| SCHEMBL4894490 | 0.77 | HRH3 (0.51) | HRH3HTR1AGRIN2DGRIN3BADRA1D | |
| SCHEMBL8113980 | 0.75 | HTR1A (0.61) | HTR1ASLC6A4GRIN2DGRIN3BADRA1D | |
| SCHEMBL7984081 | 0.75 | HTR1A (0.61) | HTR1ASLC6A4GRIN2DGRIN3BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576766-A1 | Propanolamine derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1994-01-05 | — | — | EP | disclosed |