Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753859 | 1.00 | HTR1A (0.61) | HTR1ASLC6A4SLC6A3 | |
| SCHEMBL2722580 | 0.95 | HTR1A (0.63) | HTR1ASLC6A4SLC6A3 | |
| SCHEMBL8113980 | 0.88 | HTR1A (0.61) | HTR1ASLC6A4SLC6A3 | |
| SCHEMBL7984081 | 0.88 | HTR1A (0.61) | HTR1ASLC6A4SLC6A3 | |
| SCHEMBL6980055 | 0.88 | GRIN2D (0.56) | SLC6A4SLC6A3 | |
| SCHEMBL10869155 | 0.86 | HRH3 (0.57) | HTR1ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10869348 | 0.85 | HRH3 (0.56) | HTR1ASLC6A4SLC6A3 | |
| SCHEMBL7428354 | 0.84 | GAA (0.73) | HTR1ASLC6A4SLC6A3 | |
| Prozapine SCHEMBL25765 | 0.83 | ALDH1A1 (0.66) | SLC6A3 | |
| Fenpiprane SCHEMBL24507 | 0.83 | ALDH1A1 (0.66) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100378108-C | Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them | SUVEN PHARMACEUTICALS LTD (IN) | 2008-04-02 | — | — | CN | claimed |
| CN-1662544-A | Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them | SUVEN PHARMACEUTICALS LTD (IN) | 2005-08-31 | — | — | CN | claimed |
| CN-114560892-A | Chiral tridentate nitrogen phosphine ligand synthesized based on ferrocene skeleton and application thereof | 广东工业大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113226313-A | Sustained release compositions comprising trihexyphenidyl | 卡希夫生物科学有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111044663-A | Method for determining concentration of diphenhydrasol in blood plasma by liquid chromatography-mass spectrometry | 南京立顺康达医药科技有限公司 | 2020-04-21 | — | — | CN | disclosed |
| EP-3510092-A1 | PLASTIC COMPOSITION, PRODUCTION METHOD, AND USE OF SAME | ATP Aicher + Tröbs Produktentwicklung GmbH (DE) | 2019-07-17 | — | — | EP | disclosed |
| WO-2018141587-A1 | PLASTIC COMPOSITION, PRODUCTION METHOD, AND USE OF SAME | ATP Aicher + Tröbs Produktentwicklung GmbH (DE) | 2018-08-09 | — | — | WO | disclosed |
| CN-100378108-C | Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them | SUVEN PHARMACEUTICALS LTD (IN) | 2008-04-02 | — | — | CN | disclosed |
| CN-1662544-A | Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them | SUVEN PHARMACEUTICALS LTD (IN) | 2005-08-31 | — | — | CN | disclosed |
| EP-0634932-B1 | METHOD FOR REDUCING INTRAOCULAR PRESSURE IN THE MAMMALIAN EYE BY ADMINISTRATION OF MUSCARINIC ANTAGONISTS | ALLERGAN INC (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-0634932-A1 | METHOD FOR REDUCING INTRAOCULAR PRESSURE IN THE MAMMALIAN EYE BY ADMINISTRATION OF MUSCARINIC ANTAGONISTS | ALLERGAN, INC. (US) | 1995-01-25 | — | — | EP | disclosed |