Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16839697 | 0.92 | SMN1; SMN2 (0.51) | SMN1; SMN2MMP8PPIDALDH1A1RECQL | |
| SCHEMBL2171018 | 0.84 | PPID (0.66) | SMN1; SMN2MMP8PPIDALDH1A1RECQL | |
| SCHEMBL24241874 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2MMP8PPIDALDH1A1RECQL | |
| SCHEMBL16839699 | 0.83 | KCNQ2 (0.49) | SMN1; SMN2KMT2AGAATHRB | |
| SCHEMBL16839015 | 0.81 | MEN1 (0.42) | SMN1; SMN2MMP8PPIDALDH1A1LMNA | |
| SCHEMBL13731240 | 0.80 | RIPK1 (0.53) | SMN1; SMN2MMP8RIPK1LMNAMEN1 | |
| SCHEMBL16838997 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2MMP8ALDH1A1MEN1KMT2A | |
| SCHEMBL2226 | 0.80 | MYC (0.46) | SMN1; SMN2MMP8ALDH1A1GAAKDM4E | |
| SCHEMBL1492859 | 0.79 | MMP8 (0.65) | SMN1; SMN2MMP8PPIDALDH1A1RECQL | |
| SCHEMBL6044415 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2MMP8ALDH1A1RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |