Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186546 | 0.84 | CYP2C19 (0.46) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| SCHEMBL11186153 | 0.82 | NAAA (0.43) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| Cyclohexane SCHEMBL27646533 | 0.82 | NAAA (0.58) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| SCHEMBL22213807 | 0.82 | NAAA (0.58) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| SCHEMBL3472508 | 0.82 | NAAA (0.58) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| SCHEMBL7429306 | 0.80 | NAAA (0.47) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| SCHEMBL3473161 | 0.80 | NAAA (0.56) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| SCHEMBL28529713 | 0.79 | NAAA (0.69) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| Adipic Acid SCHEMBL29034391 | 0.79 | NAAA (0.69) | NAAACYP2C19SMN1; SMN2EPHX1HTT | |
| SCHEMBL9469654 | 0.79 | NAAA (0.64) | NAAACYP2C19SMN1; SMN2EPHX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |