Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614518 | 0.81 | NAAA (0.54) | NAAAEPHX1HTTCACNA1BCYP2C19 | |
| SCHEMBL22859599 | 0.81 | EPHX1 (0.56) | NAAAEPHX1HTTCACNA1BCYP2C19 | |
| SCHEMBL7440996 | 0.80 | NAAA (0.49) | NAAAEPHX1HTTCYP2C19SMN1; SMN2 | |
| SCHEMBL7433510 | 0.80 | MEN1 (0.44) | EPHX1SMN1; SMN2EPHX2KDM4EMAPT | |
| SCHEMBL12581334 | 0.79 | MAOA (0.41) | GAAEPHX2MAPT | |
| SCHEMBL27787500 | 0.78 | NAAA (0.46) | NAAAEPHX1HTTCACNA1BCYP2C19 | |
| Hydrochloric Acid SCHEMBL13269542 | 0.78 | MAOA (0.40) | GAAEPHX2MAPT | |
| SCHEMBL5884644 | 0.76 | TSHR (0.44) | EPHX2KDM4E | |
| SCHEMBL3809747 | 0.76 | MAOA (0.39) | GAAEPHX2MAPT | |
| SCHEMBL5283279 | 0.76 | EPHX1 (0.52) | NAAAEPHX1HTTCACNA1BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |