Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20481318 | 0.83 | CHRM2 (0.53) | ALDH1A1GAALMNAKDM4EKMT2A | |
| SCHEMBL7539952 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GAALMNAKDM4EKMT2A | |
| SCHEMBL13114819 | 0.80 | MAPT (0.62) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7448825 | 0.80 | KDM4E (0.45) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL13114879 | 0.78 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL7436584 | 0.78 | CYP2C19 (0.49) | ALDH1A1GAAMAPTLMNAKDM4E | |
| Phenylacetic Acid SCHEMBL20481306 | 0.76 | CHRM2 (0.46) | ALDH1A1GAALMNAKDM4EKMT2A | |
| SCHEMBL7435164 | 0.76 | HPGD (0.50) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL10771702 | 0.75 | MAPT (0.57) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL4279296 | 0.75 | MAPT (0.57) | ALDH1A1GAAMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |