Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20481318 | 0.87 | CHRM2 (0.53) | ALDH1A1KDM4ELMNACHRM2CHRM1 | |
| SCHEMBL7448825 | 0.84 | KDM4E (0.45) | ALDH1A1KDM4ELMNACHRM2CHRM1 | |
| SCHEMBL7436584 | 0.82 | CYP2C19 (0.49) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL7441269 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EHTTLMNAMEN1 | |
| SCHEMBL7435164 | 0.80 | HPGD (0.50) | ALDH1A1KDM4ELMNACYP1A2CYP3A4 | |
| Phenylacetic Acid SCHEMBL20481306 | 0.80 | CHRM2 (0.46) | ALDH1A1KDM4ELMNACYP1A2CHRM2 | |
| SCHEMBL13114821 | 0.78 | NPY2R (0.57) | ALDH1A1KDM4ELMNACHRM2CHRM1 | |
| SCHEMBL13114822 | 0.78 | NPY2R (0.57) | ALDH1A1KDM4ELMNACHRM2CHRM1 | |
| SCHEMBL13114829 | 0.78 | NPY2R (0.57) | ALDH1A1KDM4ELMNACHRM2CHRM1 | |
| SCHEMBL13114885 | 0.76 | CHRM2 (0.46) | ALDH1A1KDM4ELMNACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |