Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436584 | 0.83 | CYP2C19 (0.49) | ALDH1A1MEN1KMT2ACYP1A2POLB | |
| SCHEMBL20481318 | 0.81 | CHRM2 (0.53) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL7539952 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7448825 | 0.78 | KDM4E (0.45) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL7441269 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL8864610 | 0.75 | HPGD (0.61) | HPGDRECQLALDH1A1MEN1KMT2A | |
| SCHEMBL5726107 | 0.74 | HPGD (0.60) | HPGDRECQLALDH1A1MEN1KMT2A | |
| Phenylacetic Acid SCHEMBL20481306 | 0.74 | CHRM2 (0.46) | ALDH1A1MEN1KMT2ACYP1A2POLB | |
| SCHEMBL7449492 | 0.74 | PANK3 (0.42) | HPGDRECQLALDH1A1MEN1KMT2A | |
| SCHEMBL20481400 | 0.70 | LMNA (0.71) | ALDH1A1MEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |