Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.51 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757017 | 0.84 | LMNA (0.61) | KDM4ECA12CA9CYP2C9ALDH1A1 | |
| SCHEMBL30028309 | 0.76 | ALDH2 (0.52) | KDM4ECYP2C19EYA3CYP2C9ALDH1A1 | |
| SCHEMBL183071 | 0.76 | ALDH2 (0.52) | KDM4ECYP2C19EYA3CYP2C9ALDH1A1 | |
| SCHEMBL578354 | 0.76 | KDM4E (0.53) | KDM4ECYP2C19CA12CA9CYP2C9 | |
| SCHEMBL29695571 | 0.75 | KDM4E (1.00) | KDM4ECYP2C19CA12CA9CYP2C9 | |
| SCHEMBL5459905 | 0.75 | KDM4E (1.00) | KDM4ECYP2C19CA12CA9CYP2C9 | |
| Hydrochloric Acid SCHEMBL28410509 | 0.74 | KDM4E (0.52) | KDM4ECYP2C19CA12CA9CYP2C9 | |
| SCHEMBL7648203 | 0.74 | KDM4E (0.52) | KDM4ECYP2C19CA12CA9CYP2C9 | |
| SCHEMBL12217614 | 0.74 | MAOB (0.44) | KDM4ECA12CA9CYP2C9ALDH1A1 | |
| SCHEMBL13028651 | 0.73 | CYP2C19 (0.51) | KDM4ECYP2C19EYA3CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751855-B1 | DIKETOPYRROLOPYRROLE OLIGOMERS AND COMPOSITIONS, COMPRISING DIKETOPYRROLOPYRROLE OLIGOMERS | BASF SE (DE) | 2020-10-28 | — | — | EP | disclosed |
| CN-105646414-A | Synthetic method of 6-hydroxyl-2-methylbenzofuran type compound | 和记黄埔医药（苏州）有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |
| US-3984470-A | ANTIDEPRESSIVE AND ANTIAGGRESSIVE AGENTS | LABAZ (FR) | 1976-10-05 | — | — | US | disclosed |
| US-3931240-A | ANTIDEPRESSANT, ANTIAGGRESSION | LABAZ (FR) | 1976-01-06 | — | — | US | disclosed |