Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | NQO1 | P15559 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28410509 | 0.98 | KDM4E (0.52) | KDM4ENQO1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL1180659 | 0.82 | KDM4E (0.62) | KDM4ECYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL29155467 | 0.76 | AHR (0.46) | KDM4ENQO1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL20657033 | 0.76 | KDM4E (0.55) | KDM4ENQO1CYP3A4ALDH1A1KMT2A | |
| SCHEMBL28961807 | 0.76 | KDM4E (0.50) | KDM4ENQO1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL744133 | 0.76 | KDM4E (0.60) | KDM4ENQO1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL29872 | 0.75 | KDM4E (0.69) | KDM4ENQO1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL29379994 | 0.75 | KDM4E (0.69) | KDM4ENQO1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL7737431 | 0.75 | KDM4E (0.69) | KDM4ENQO1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL11778619 | 0.73 | PTPN1 (0.49) | KDM4ENQO1CYP3A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109549918-B | Ophthalmic medicine composition, ophthalmic medicine box and medical application thereof | 沈阳兴齐眼药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-219001692-U | Balloon device containing estrogen for preventing uterine cavity adhesion | 深圳市罗湖区妇幼保健院 | 2023-05-12 | — | — | CN | claimed |
| CN-114432231-A | Ophthalmic pharmaceutical composition, ophthalmic medicine box and medical application thereof | 沈阳兴齐眼药股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| EP-2751160-B1 | EPOXY RESINS WITH HIGH THERMAL STABILITY AND TOUGHNESS | HUNTSMAN ADV MAT AMERICAS INC (US) | 2016-09-28 | — | — | EP | claimed |
| EP-2751160-A1 | EPOXY RESINS WITH HIGH THERMAL STABILITY AND TOUGHNESS | Huntsman Advanced Materials Americas LLC (US) | 2014-07-09 | — | — | EP | claimed |
| US-20140069583-A1 | Epoxy Resins With High Thermal Stability and Toughness | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC | 2014-03-13 | — | — | US | claimed |
| CN-102199138-B | Preparation method for 6, 7-di-substituted-2, 3 dihydrobenzofuran | SHANGHAI DESANO PHARMACEUTICALS HOLDING CO LTD | 2013-06-12 | — | — | CN | claimed |
| WO-2012158363-A1 | EPOXY RESINS WITH HIGH THERMAL STABILITY AND TOUGHNESS | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2012-11-22 | — | — | WO | claimed |
| CN-102199138-A | Preparation method for 6, 7-di-substituted-2, 3 dihydrobenzofuran | SHANGHAI DESANO PHARMACEUTICALS HOLDING CO LTD | 2011-09-28 | — | — | CN | claimed |
| US-20040022834-A1 | Pharmaceutical oxan preparation | PIERRE FABRE MEDICAMENT (FR) | 2004-02-05 | — | — | US | claimed |
| US-4564691-A | Process for preparing substituted 2,3-dihydrobenzofuran | ENICHIMICA SECONDARIA S.P.A. (IT) | 1986-01-14 | — | — | US | claimed |
| EP-0127208-A1 | Process for preparing substituted 2,3-dihydrobenzofuran | ENICHIMICA SECONDARIA S.p.A. (IT) | 1984-12-05 | — | — | EP | claimed |
| US-20250019374-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | SYGNATURE DISCOVERY LIMITED (GB) | 2025-01-16 | — | — | US | disclosed |
| EP-4430038-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Calico Life Sciences LLC (US) | 2024-09-18 | — | — | EP | disclosed |
| US-20240293482-A1 | COMPOSITIONS AND METHODS FOR TREATING BIOFILMS, INFECTIONS AND PERIODONTITIS | ETHEIM BIOTICS LLC (US) | 2024-09-05 | — | — | US | disclosed |
| CN-118525016-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2024-08-20 | — | — | CN | disclosed |
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| US-5262418-A | Laxatives, gastrointestinal disorders | TANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-16 | — | — | US | disclosed |
| US-4014906-A | Process for the manufacture of anthraquinone compounds | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3969372-A | 2,3-Dihydro-3,3-dimethyl-2,5-benzofurandiol from isobutyraldehyde and benzoquinone | EASTMAN KODAK COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250019374-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | PTPN5, PTPN1, PTPN3 | KDM4E 505/4885NQO1 2387/4885CYP3A4 3604/4885 |
| US-20040022834-A1 | Pharmaceutical oxan preparation | OXA1L, OSTC, OTC | KDM4E 2740/4885NQO1 305/4885CYP3A4 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.