Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.74 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.74 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586009 | 0.95 | MEN1 (0.82) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5494252 | 0.95 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL3247339 | 0.95 | MEN1 (0.82) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL6858437 | 0.95 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL4585220 | 0.95 | MEN1 (0.82) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL3242127 | 0.94 | MEN1 (0.84) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL3242116 | 0.94 | MEN1 (0.84) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL3236700 | 0.94 | MEN1 (0.84) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL4593681 | 0.92 | MEN1 (0.73) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL4586153 | 0.91 | PDE4A (0.71) | MEN1KMT2ACHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |