Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | F13A1 | P00488 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444387 | 0.84 | RAB9A (0.55) | RAB9ANPC1ALDH1A1POLBGAA | |
| SCHEMBL3786992 | 0.82 | GSK3B (0.53) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL7440297 | 0.82 | KMT2A (0.54) | RAB9APTPN1NPC1ALDH1A1POLB | |
| SCHEMBL3323642 | 0.82 | GSK3B (0.53) | RAB9AALDH1A1POLBGAAMAPT | |
| SCHEMBL1945591 | 0.82 | MTNR1A (0.59) | KDM4ERAB9APTPN1NPC1ALDH1A1 | |
| SCHEMBL9837130 | 0.82 | PTPN1 (0.52) | HSD17B3KDM4ERAB9APTPN1NPC1 | |
| SCHEMBL7440946 | 0.81 | ALDH1A1 (0.53) | KDM4EF13A1RAB9ANPC1ALDH1A1 | |
| SCHEMBL8752513 | 0.81 | ALDH1A1 (0.66) | KDM4ERAB9AALDH1A1TDP1L3MBTL1 | |
| Methane SCHEMBL11374227 | 0.80 | MTNR1A (0.57) | KDM4ERAB9APTPN1NPC1ALDH1A1 | |
| Methane SCHEMBL9835792 | 0.80 | NPC1 (0.50) | HSD17B3KDM4ERAB9APTPN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |