Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434663 | 0.82 | ALDH1A1 (0.42) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL2058361 | 0.81 | ALDH1A1 (0.55) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL5673051 | 0.80 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL43742 | 0.79 | KMT2A (0.61) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL11931642 | 0.79 | LTA4H (0.49) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL11183595 | 0.79 | PRSS1 (0.50) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL4896084 | 0.78 | PRSS1 (0.61) | KMT2AALDH1A1MAPTLMNAHTT | |
| Adipic Acid SCHEMBL28248016 | 0.78 | PRSS1 (0.57) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL7569171 | 0.78 | PRSS1 (0.57) | KMT2AALDH1A1MAPTLMNAHTT | |
| SCHEMBL10352222 | 0.77 | CYP19A1 (0.44) | KMT2AALDH1A1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |