Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | ADH1B | P00325 | 1/20 | 0.47 |
| ▸ | ADH1C | P00326 | 1/20 | 0.47 |
| ▸ | ADH1A | P07327 | 1/20 | 0.47 |
| ▸ | ADH7 | P40394 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3159306 | 0.77 | HSD17B10 (0.52) | HSD17B10ABCB1ABCG2HPGDKDM4E | |
| SCHEMBL893345 | 0.77 | HSD17B10 (0.60) | HSD17B10ABCB1ABCG2HPGDKDM4E | |
| SCHEMBL28864992 | 0.76 | ABCB1 (0.50) | HSD17B10ABCB1ABCG2HPGDKDM4E | |
| SCHEMBL2614335 | 0.75 | AR (0.40) | HSD17B10HPGDKDM4EALDH1A1POLB | |
| SCHEMBL11070078 | 0.75 | ADRA2B (0.35) | ABCB1ABCG2HTTPOLBMAPT | |
| SCHEMBL8503692 | 0.75 | HSD17B10 (0.49) | HSD17B10ABCB1ABCG2HPGDKDM4E | |
| SCHEMBL19495506 | 0.75 | HSD17B10 (0.53) | HSD17B10ABCB1ABCG2HPGDKDM4E | |
| SCHEMBL5790165 | 0.74 | HSD17B10 (0.57) | HSD17B10ABCB1ABCG2HPGDKDM4E | |
| SCHEMBL19495269 | 0.73 | ABCB1 (0.51) | HSD17B10ABCB1ABCG2HPGDKDM4E | |
| SCHEMBL7760447 | 0.73 | KDM4E (0.56) | HSD17B10ABCB1ABCG2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861233-A1 | N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES | G.D. SEARLE & CO. (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997018190-A1 | N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES | G.D. SEARLE & CO. (US) | 1997-05-22 | — | — | WO | disclosed |
| WO-1995006061-A1 | RETROVIRAL PROTEASE INHIBITORS AND COMBINATIONS THEREOF | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |