Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.55 |
| ▸ | LTA4H | P09960 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499435 | 0.87 | ACE (0.49) | ACEACE2TAAR1 | |
| SCHEMBL14903366 | 0.86 | ACE (0.57) | ACEACE2LTA4HTSHRTAAR1 | |
| SCHEMBL14903323 | 0.86 | ACE (0.57) | ACEACE2LTA4HTSHRTAAR1 | |
| SCHEMBL11060360 | 0.82 | LTA4H (0.61) | ACEACE2LTA4HTSHR | |
| SCHEMBL18620886 | 0.82 | ACE (0.69) | ACEACE2TSHRTAAR1 | |
| SCHEMBL20485193 | 0.82 | ACE (0.69) | ACEACE2TSHRTAAR1 | |
| SCHEMBL8279537 | 0.81 | ACE (0.61) | ACEACE2LTA4HTSHR | |
| SCHEMBL14428591 | 0.81 | ACE (0.61) | ACEACE2LTA4HTSHR | |
| SCHEMBL8258582 | 0.81 | ACE (0.61) | ACEACE2LTA4HTSHR | |
| SCHEMBL14903368 | 0.81 | ACE (0.53) | ACEACE2LTA4HTSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748333-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0748333-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023809-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |