Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180131 | 0.84 | METAP2 (0.40) | CA12CA1CA9 | |
| SCHEMBL3672272 | 0.84 | CYP2C9 (0.48) | NOS1ALDH1A1MAPTALOX12CYP2C9 | |
| SCHEMBL10890947 | 0.81 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL20804279 | 0.81 | HDAC1 (0.36) | MAPT | |
| SCHEMBL207271 | 0.80 | PRSS1 (0.37) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL2717977 | 0.80 | PRSS1 (0.55) | SLC11A2NOS1LMNAALDH1A1CYP2D6 | |
| SCHEMBL31540904 | 0.80 | LOXL2 (0.55) | SLC11A2NOS1LMNAALDH1A1CYP2D6 | |
| SCHEMBL14470339 | 0.80 | ALDH1A1 (0.46) | SLC11A2NOS1LMNAALDH1A1CYP2D6 | |
| SCHEMBL16089570 | 0.80 | HDAC1 (0.35) | SLC11A2LMNA | |
| SCHEMBL16041872 | 0.80 | IGF1R (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063819-A | PROTECTING NEURONS FROM DAMAGE BY ADMINISTERING TO HUMANS POLYGUADINO COMPOUNDS | CYPROS PHARMACEUTICAL CORP. (US) | 2000-05-16 | — | — | US | disclosed |