Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183623 | 0.94 | CYP1A2 (0.53) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10851467 | 0.92 | CYP1A2 (0.52) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| SCHEMBL13411252 | 0.91 | GAA (0.54) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| SCHEMBL13411251 | 0.91 | GAA (0.54) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| SCHEMBL13411255 | 0.91 | GAA (0.54) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| SCHEMBL31442225 | 0.88 | CYP1A2 (0.55) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| SCHEMBL285776 | 0.86 | LTA4H (0.50) | GAALTA4HALDH1A1KMT2AMAPT | |
| SCHEMBL16948556 | 0.86 | CYP1A2 (0.53) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| SCHEMBL837763 | 0.86 | ALDH1A1 (0.57) | GAACYP1A2LTA4HALDH1A1KMT2A | |
| SCHEMBL1392816 | 0.85 | LTA4H (0.51) | GAALTA4HALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |