Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064581 | 0.92 | KMT2A (1.00) | KMT2ANPC1RAB9ACA12CA9 | |
| SCHEMBL4319665 | 0.88 | KMT2A (0.64) | KMT2ANPC1RAB9AMEN1L3MBTL1 | |
| SCHEMBL7442885 | 0.84 | KMT2A (0.77) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL9347002 | 0.84 | KMT2A (0.72) | KMT2ANPC1RAB9ACA12CA9 | |
| SCHEMBL9193944 | 0.80 | KMT2A (0.71) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL19002583 | 0.80 | RAB9A (0.58) | KMT2ANPC1RAB9AMTORCA12 | |
| SCHEMBL4072151 | 0.80 | NPC1 (0.85) | KMT2ANPC1RAB9ACA12CA9 | |
| SCHEMBL414702 | 0.79 | NPC1 (0.60) | KMT2ANPC1RAB9ACA12CA9 | |
| SCHEMBL12290151 | 0.78 | NPC1 (0.82) | KMT2ANPC1RAB9ACA12CA9 | |
| SCHEMBL14219225 | 0.78 | KMT2A (0.74) | KMT2ANPC1RAB9AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |