Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088217 | 0.81 | IDO1 (0.35) | KMT2AADRA2AHTTCYP2D6LMNA | |
| SCHEMBL1201089 | 0.79 | TRPA1 (0.43) | MIFALDH1A1L3MBTL1TAAR1THRB | |
| SCHEMBL28792130 | 0.79 | TRPA1 (0.43) | MIFALDH1A1L3MBTL1TAAR1THRB | |
| SCHEMBL7306869 | 0.78 | KMT2A (0.42) | ALDH1A1L3MBTL1KMT2ATHRBCYP2D6 | |
| SCHEMBL188510 | 0.78 | KMT2A (0.42) | ALDH1A1L3MBTL1KMT2ATHRBCYP2D6 | |
| SCHEMBL7704413 | 0.78 | KMT2A (0.42) | ALDH1A1L3MBTL1KMT2ATHRBCYP2D6 | |
| SCHEMBL4602744 | 0.75 | NPSR1 (0.40) | ALDH1A1KMT2ATAAR1CYP2D6CA12 | |
| SCHEMBL11176872 | 0.74 | CYP2D6 (0.34) | KMT2ACYP2D6LMNA | |
| SCHEMBL27418681 | 0.74 | SRC (0.39) | ALDH1A1L3MBTL1KMT2ACYP2D6LMNA | |
| SCHEMBL9165582 | 0.73 | L3MBTL1 (0.43) | MIFALDH1A1L3MBTL1KMT2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542525-B1 | Antithrombotic agents | LILLY CO ELI (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0837071-A1 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0685489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0684258-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5430023-A | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5252566-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| CN-1074438-A | Antithrombotic agent | LILLY CO ELI (US) | 1993-07-21 | — | — | CN | disclosed |
| EP-0542525-A2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0479489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1992-04-08 | — | — | EP | disclosed |