Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188510 | 1.00 | KMT2A (0.42) | KMT2ATHRBCYP3A4EPHX1ACP3 | |
| SCHEMBL7306869 | 1.00 | KMT2A (0.42) | KMT2ATHRBCYP3A4EPHX1ACP3 | |
| SCHEMBL10581191 | 0.80 | KMT2A (0.41) | KMT2ATHRBCYP3A4EPHX1ACP3 | |
| SCHEMBL7442974 | 0.78 | MIF (0.35) | KMT2ATHRBCYP3A4ALDH1A1LMNA | |
| SCHEMBL2796305 | 0.78 | AOC3 (0.41) | KMT2AALDH1A1GAALMNA | |
| SCHEMBL198465 | 0.77 | TSHR (0.46) | KMT2ATHRBCYP3A4EPHX1TSHR | |
| SCHEMBL8692714 | 0.77 | THRB (0.40) | KMT2ATHRBCYP3A4EPHX1TSHR | |
| SCHEMBL198464 | 0.77 | TSHR (0.46) | KMT2ATHRBCYP3A4EPHX1TSHR | |
| SCHEMBL27625768 | 0.77 | TSHR (0.46) | KMT2ATHRBCYP3A4EPHX1TSHR | |
| SCHEMBL11176872 | 0.77 | CYP2D6 (0.34) | KMT2ATSHRLMNACYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867231-B1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F I S - FABBRICA ITALIANA SINTETICI S P A (IT) | 2017-01-04 | — | — | EP | claimed |
| US-20160200744-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2016-07-14 | — | — | US | claimed |
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2015-12-03 | — | — | US | claimed |
| EP-2867231-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2015-05-06 | — | — | EP | claimed |
| WO-2014128022-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2014-08-28 | — | — | WO | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | claimed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | claimed |
| US-9981910-B2 | Substituted pyrrolidines and methods of use | ABBVIE S.Á.R.L. (LU) | 2018-05-29 | — | — | US | disclosed |
| US-9932361-B2 | Convenient process for the preparation of statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2018-04-03 | — | — | US | disclosed |
| EP-2867231-B1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F I S - FABBRICA ITALIANA SINTETICI S P A (IT) | 2017-01-04 | — | — | EP | disclosed |
| US-20160200744-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2016-07-14 | — | — | US | disclosed |
| US-9315470-B2 | Convenient process for the preparation of statins | F.I.S.—Fabbrica Italiana Sintetiei S.p.A. (IT) | 2016-04-19 | — | — | US | disclosed |
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2015-12-03 | — | — | US | disclosed |
| EP-0684258-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5430023-A | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0623129-A1 | 2,2-DIALKYL- AND 2,2-DIALKYL-3,4-DIHYDRO-3-HYDROXY-2H-1-BENZOPYR ANS, THEIR USE AS PHARMACEUTICALS | Novartis AG (CH) | 1994-11-09 | — | — | EP | disclosed |
| WO-1994012493-A1 | 2,2-DIALKYL- AND 2,2-DIALKYL-3,4-DIHYDRO-3-HYDROXY-2H-1-BENZOPYR ANS, THEIR USE AS PHARMACEUTICALS | SANDOZ, LTD. (CH) | 1994-06-09 | — | — | WO | disclosed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | HMGCR, PCSK9, FDPS | KMT2A 2672/4885THRB 4060/4885CYP3A4 38/4885 |
| US-20160200744-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | HMGCR, PCSK9, FDPS | KMT2A 2672/4885THRB 4060/4885CYP3A4 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.