Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPA3 | P15088 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508655 | 0.83 | TSHR (0.49) | MMP8MEN1KMT2A | |
| SCHEMBL12345534 | 0.81 | LDHA (0.41) | MDM2PTGS1CPA1MMECYP2C9 | |
| SCHEMBL7239119 | 0.79 | CYP1A2 (0.55) | MDM2CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL392827 | 0.78 | CYP1A2 (0.70) | MDM2CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL14883636 | 0.77 | MMP9 (0.44) | MMP8CPA1MMEMEN1POLB | |
| SCHEMBL2565008 | 0.76 | CYP1A2 (0.52) | MDM2CYP1A2ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL7304155 | 0.76 | CYP1A2 (0.67) | MDM2CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL27876635 | 0.76 | CYP1A2 (0.67) | MDM2CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL28314499 | 0.76 | CYP1A2 (0.67) | MDM2CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL28377626 | 0.76 | CYP1A2 (0.67) | MDM2CYP1A2ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |