Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 3/20 | 0.70 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.70 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.70 |
| ▸ | LTA4H | P09960 | 2/20 | 0.69 |
| ▸ | GCGR | P47871 | 2/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 7/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445638 | 0.99 | LTA4H (0.70) | PSMB1PSMB5PSMB2LTA4HGCGR | |
| SCHEMBL7352552 | 0.94 | LTA4H (0.65) | PSMB1PSMB5PSMB2LTA4HGCGR | |
| SCHEMBL7439685 | 0.93 | LTA4H (0.63) | PSMB1PSMB5PSMB2LTA4HGCGR | |
| SCHEMBL8711348 | 0.85 | LTA4H (0.76) | PSMB1PSMB5PSMB2LTA4HGCGR | |
| SCHEMBL7748549 | 0.85 | ESR1 (0.66) | PSMB1PSMB5PSMB2LTA4HGCGR | |
| SCHEMBL3092657 | 0.84 | ESR1 (0.65) | PSMB1PSMB5PSMB2KCNH2ALDH1A1 | |
| SCHEMBL13305534 | 0.83 | LTA4H (0.97) | PSMB1PSMB5PSMB2LTA4HGCGR | |
| SCHEMBL8599886 | 0.83 | ESR1 (0.65) | PSMB1PSMB5PSMB2LTA4HGCGR | |
| SCHEMBL7738182 | 0.83 | ESR1 (0.64) | PSMB1PSMB5PSMB2LTA4HKCNH2 | |
| SCHEMBL8588964 | 0.82 | LTA4H (0.64) | PSMB1PSMB5PSMB2LTA4HGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |