Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435244 | 0.79 | NPY2R (0.52) | SLC1A3SLC1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL7443501 | 0.79 | LMNA (0.46) | HRH1CCR3KCNH2MAPTALDH1A1 | |
| SCHEMBL7435932 | 0.79 | ITGB3 (0.50) | FFAR1ACACBMAPTALDH1A1KDM4E | |
| SCHEMBL7442245 | 0.79 | KDM4E (0.44) | FFAR1ACACBMAPTALDH1A1LMNA | |
| SCHEMBL7442249 | 0.79 | KDM4E (0.44) | FFAR1ACACBMAPTALDH1A1LMNA | |
| SCHEMBL7440141 | 0.78 | CHRM2 (0.46) | MAPTALDH1A1KDM4ECHRM4 | |
| SCHEMBL7439832 | 0.75 | KDM4E (0.43) | ALDH1A1KDM4ECHRM4 | |
| SCHEMBL7444850 | 0.75 | NPY2R (0.42) | SLC1A3SLC1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL7442787 | 0.74 | KDM4E (0.48) | KCNH2SLC1A2KDM4ECHRM4CXCR3 | |
| SCHEMBL7444975 | 0.74 | PANK3 (0.42) | SLC1A3SLC1A2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |