Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 5/20 | 0.38 |
| ▸ | BRD1 | O95696 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.36 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.36 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066950 | 0.85 | CYP2A6 (0.44) | RORCENPP3CDC7BRPF1BRD1 | |
| SCHEMBL7491020 | 0.81 | BRPF1 (0.42) | RORCBRPF1BRD1BRPF3NTRK1 | |
| SCHEMBL1313567 | 0.78 | TSHR (0.46) | RORCENPP3CDC7BRPF1 | |
| SCHEMBL25292537 | 0.76 | MAPT (0.49) | MAOA | |
| SCHEMBL10053515 | 0.76 | BRPF1 (0.45) | ENPP3CDC7BRPF1BRD1BRD4 | |
| SCHEMBL2433002 | 0.75 | NTRK1 (0.42) | NTRK1CNR1 | |
| Bromide SCHEMBL7489164 | 0.75 | ENPP3 (0.39) | RORCENPP3CDC7BRPF1ALB | |
| SCHEMBL6606799 | 0.75 | BRPF1 (0.51) | BRPF1MAOA | |
| SCHEMBL18112916 | 0.75 | RXFP1 (0.47) | MAOA | |
| SCHEMBL14757769 | 0.75 | MAOA (0.38) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079396-C | Aromatic amidine derivatives useful as selective thrombin inhibitors | C & C RES LAB (KR) | 2002-02-20 | — | — | CN | disclosed |
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| CN-1219932-A | Aromatic amidine derivatives useful as selective thrombin inhibitors | C & C RESEARCH LAB (KR) | 1999-06-16 | — | — | CN | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |