Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913404 | 0.98 | HDAC8 (0.68) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10495286 | 0.98 | HDAC8 (0.68) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29740524 | 0.95 | ALDH1A1 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2084857 | 0.95 | ALDH1A1 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| Ethylene SCHEMBL9101813 | 0.92 | ALDH1A1 (0.56) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| Ethylene Glycol SCHEMBL7141967 | 0.90 | ALDH1A1 (0.55) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10655522 | 0.88 | HDAC8 (0.62) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL133683 | 0.87 | KMT2A (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15500771 | 0.85 | ALDH1A1 (0.71) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1795851 | 0.84 | HDAC8 (0.67) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796140-A2 | Stabilized Sulforaphane | Pharmagra Labs, Inc. (US) | 2014-10-29 | — | — | EP | disclosed |
| EP-0511271-A1 | THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1992-11-04 | — | — | EP | disclosed |
| EP-0511270-A1 | NEW THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1992-11-04 | — | — | EP | disclosed |
| WO-1991010656-A1 | THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-07-25 | — | — | WO | disclosed |
| WO-1991010657-A1 | NEW THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-07-25 | — | — | WO | disclosed |
| US-RE32868-E | Antihyperlipidemic compositions | RESEARCH CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4395417-A | Antihyperlipidemic compositions | RESEARCH CORPORATION (US) | 1983-07-26 | — | — | US | disclosed |