Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740524 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ACHEKMT2AHSD17B10MEN1 | |
| Ethylene SCHEMBL9101813 | 0.97 | ALDH1A1 (0.56) | ALDH1A1ACHEKMT2AHSD17B10MEN1 | |
| Ethylene Glycol SCHEMBL7141967 | 0.95 | ALDH1A1 (0.55) | ALDH1A1ACHEKMT2AHSD17B10MEN1 | |
| SCHEMBL7443883 | 0.95 | HDAC8 (0.65) | ALDH1A1ACHEKMT2AHSD17B10MEN1 | |
| SCHEMBL10913404 | 0.93 | HDAC8 (0.68) | ALDH1A1KMT2AMEN1HDAC8HDAC3 | |
| SCHEMBL10495286 | 0.93 | HDAC8 (0.68) | ALDH1A1KMT2AMEN1HDAC8HDAC3 | |
| SCHEMBL133683 | 0.89 | KMT2A (0.59) | ALDH1A1KMT2AHSD17B10MEN1HDAC8 | |
| SCHEMBL12134373 | 0.86 | ALDH1A1 (0.66) | ALDH1A1ACHEKMT2AHSD17B10MEN1 | |
| SCHEMBL11754615 | 0.85 | ALDH1A1 (0.62) | ALDH1A1ACHEKMT2AHSD17B10MEN1 | |
| SCHEMBL5041554 | 0.84 | ALDH1A1 (0.60) | ALDH1A1ACHEKMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132517-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | GOHARMONY THERAPEUTICS (SHENZHEN) CO., LTD. (CN) | 2024-04-25 | — | — | US | disclosed |
| WO-2024076635-A2 | SUPPRESSORS OF SITE IQ ELECTRON LEAK AND USES THEREOF | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2024-04-11 | — | — | WO | disclosed |
| CN-116829562-A | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳国顺康医药科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| US-20230133656-A1 | HYDROGEL COMPOSITIONS AND USES THEREOF | SHOICHET, MOLLY SANDRA (CA) | 2023-05-04 | — | — | US | disclosed |
| WO-2022171139-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 北京国鸿生物医药科技有限公司 | 2022-08-18 | — | — | WO | disclosed |
| EP-3580224-B1 | ASK1 INHIBITING AGENTS | BIOGEN MA INC (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-3580224-B1 | ASK1 INHIBITING AGENTS | BIOGEN MA INC (US) | 2022-07-13 | — | — | EP | disclosed |
| CN-110950890-B | Substituted imidazo [4,5-c ] quinoline macrocycles as multi-target kinase inhibitors | 北京赛林泰医药技术有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-20220023315-A1 | METHODS OF ACTIVATING MICROGLIAL CELLS | UNIV NEW YORK STATE RES FOUND (US) | 2022-01-27 | — | — | US | disclosed |
| US-11168095-B2 | ASK1 inhibiting agents | BIOGEN MA INC. (US) | 2021-11-09 | — | — | US | disclosed |
| EP-0511271-A1 | THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1992-11-04 | — | — | EP | disclosed |
| EP-0496700-A1 | Diphosphines containing silane groups, immobilized diphosphines and their use as hydrogenation catalysts | CIBA-GEIGY AG (CH) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991010656-A1 | THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-07-25 | — | — | WO | disclosed |
| WO-1991010657-A1 | NEW THIAZOLE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-07-25 | — | — | WO | disclosed |
| EP-0415948-A1 | PROCESS FOR PREPARING A SUBSTITUTED OR AN UNSUBSTITUTED 4(5)-($g(v)-AMINOALKYL)IMIDAZOLE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010360-A1 | PROCESS FOR PREPARING A SUBSTITUTED OR AN UNSUBSTITUTED 4(5)-(omega-AMINOALKYL)IMIDAZOLE | CEDONA PHARMACEUTICALS B.V. (NL) | 1989-11-02 | — | — | WO | disclosed |
| US-RE32868-E | Antihyperlipidemic compositions | RESEARCH CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4395417-A | Antihyperlipidemic compositions | RESEARCH CORPORATION (US) | 1983-07-26 | — | — | US | disclosed |
| US-4160862-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4021431-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133656-A1 | HYDROGEL COMPOSITIONS AND USES THEREOF | CD44, UACA, ALDH1A2 | ALDH1A1 160/4885ACHE 3731/4885KMT2A 4308/4885 |
| US-11168095-B2 | ASK1 inhibiting agents | MAP3K1, MAP3K10, MAP3K20 | ALDH1A1 2232/4885ACHE 3588/4885KMT2A 2685/4885 |
| US-20220023315-A1 | METHODS OF ACTIVATING MICROGLIAL CELLS | LPCAT3, PLAAT2, PLA2G4B | ALDH1A1 3288/4885ACHE 272/4885KMT2A 1657/4885 |
| US-20240132517-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | SRC, FLT3, BRAF | ALDH1A1 4014/4885ACHE 1427/4885KMT2A 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.