Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443077 | 0.88 | CYP2C9 (0.37) | CYP2C9 | |
| SCHEMBL7445308 | 0.87 | CYP2C9 (0.32) | CYP2C9 | |
| SCHEMBL7442732 | 0.87 | ESR1 (0.39) | CYP2C9 | |
| SCHEMBL7436844 | 0.86 | ALDH1A1 (0.32) | — | |
| SCHEMBL7438454 | 0.86 | ESR2 (0.33) | CYP2C9 | |
| SCHEMBL7444897 | 0.85 | NQO1 (0.36) | CYP2C9 | |
| SCHEMBL7445588 | 0.85 | MAPT (0.39) | CYP2C9 | |
| SCHEMBL7443923 | 0.85 | CYP2C9 (0.31) | CYP2C9 | |
| SCHEMBL7447190 | 0.84 | CYP2C9 (0.31) | CYP2C9 | |
| SCHEMBL7441942 | 0.83 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | claimed |