Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.65 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444076 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BITGA2NAMPT | |
| SCHEMBL7444051 | 0.79 | ITGB3 (1.00) | ITGB3ITGA2BITGA2 | |
| SCHEMBL9335737 | 0.73 | TPSAB1 (0.67) | ITGB3ITGA2BTPSAB1KLKB1F2 | |
| SCHEMBL6677677 | 0.72 | ITGB3 (0.70) | ITGB3ITGA2BKLKB1F2 | |
| SCHEMBL6677664 | 0.72 | ITGB3 (0.70) | ITGB3ITGA2BKLKB1F2 | |
| SCHEMBL7396971 | 0.70 | ITGB3 (1.00) | ITGB3ITGA2BITGA2 | |
| SCHEMBL7442201 | 0.69 | ITGB3 (0.81) | ITGB3ITGA2B | |
| SCHEMBL6953183 | 0.69 | ITGB3 (0.81) | ITGB3ITGA2B | |
| SCHEMBL7438065 | 0.69 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL7438102 | 0.69 | ITGB3 (0.60) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |