Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.48 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 6/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444067 | 0.85 | ITGB3 (0.65) | ITGB3ITGA2BITGA2NAMPT | |
| SCHEMBL6677682 | 0.73 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7396984 | 0.73 | ITGB3 (0.75) | ITGB3ITGA2BITGA2HDAC1HDAC8 | |
| SCHEMBL7442215 | 0.71 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL6678690 | 0.70 | ITGB3 (0.53) | ITGB3ITGA2BNAMPT | |
| SCHEMBL6676580 | 0.70 | ITGB3 (0.48) | ITGB3ITGA2BNAMPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8182682 | 0.69 | ITGB3 (0.68) | ITGB3ITGA2BITGA2HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7659033 | 0.69 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7373451 | 0.67 | PPARG (0.65) | ITGB3ITGA2BHDAC8HDAC6PPARG | |
| SCHEMBL7444173 | 0.67 | ITGB3 (0.72) | ITGB3ITGA2BITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |