Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442559 | 0.92 | KMT2A (0.41) | KDM4EPKMKMT2AALDH1A1MAPT | |
| SCHEMBL7441380 | 0.88 | ALDH1A1 (0.39) | KDM4EKMT2AALDH1A1MAPTABL1 | |
| SCHEMBL7498844 | 0.85 | KDM4E (0.50) | KDM4EPKMKMT2AALDH1A1USP30 | |
| SCHEMBL7446666 | 0.85 | ALDH1A1 (0.37) | KDM4EKMT2AALDH1A1MAPTSTS | |
| SCHEMBL7444185 | 0.84 | KDM4E (0.47) | KDM4EPKMKMT2AALDH1A1USP30 | |
| SCHEMBL7444180 | 0.84 | KDM4E (0.47) | KDM4EPKMKMT2AUSP30CHRM2 | |
| SCHEMBL7446367 | 0.81 | ITGB3 (0.48) | KDM4EPKMKMT2AUSP30STS | |
| SCHEMBL7449634 | 0.80 | ALDH1A1 (0.40) | KDM4EKMT2AALDH1A1MAPTABL1 | |
| SCHEMBL7446356 | 0.80 | KDM4E (0.49) | KDM4EPKMKMT2AUSP30STS | |
| SCHEMBL7506881 | 0.79 | NPC1 (0.47) | KDM4EALDH1A1USP30CHRM5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |