SCHEMBL744429

SCHEMBL744429

CCCCCCCCCCCCCCCCCC(=O)OC[C@@]1(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@@H]1OC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.42
LDHA P00338 1/20 0.41
EPHX2 P34913 1/20 0.40
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
SELP P16109 1/20 0.39
VEGFA P15692 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4795989 0.94 AKT1 (0.43) AKT1LDHAEPHX2CDK1CCNB1
SCHEMBL758333 0.94 AKT1 (0.43) AKT1LDHAEPHX2CDK1CCNB1
SCHEMBL10767543 0.94 AKT1 (0.43) AKT1LDHAEPHX2CDK1CCNB1
SCHEMBL3025384 0.94 AKT1 (0.43) AKT1LDHAEPHX2CDK1CCNB1
SCHEMBL15436002 0.94 AKT1 (0.43) AKT1LDHAEPHX2CDK1CCNB1
SCHEMBL15435982 0.94 AKT1 (0.43) AKT1LDHAEPHX2CDK1CCNB1
SCHEMBL6151078 0.93 TLR4 (0.42) LDHAEPHX2
SCHEMBL717379 0.93 LDHA (0.41) AKT1LDHAEPHX2CDK1CCNB1
SCHEMBL1427803 0.89 CETP (0.43) LDHA
SCHEMBL5677688 0.88 VEGFA (0.42) AKT1LDHAVEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114344196-A Oily solid cosmetic 株式会社资生堂 2022-04-15 CN claimed
US-11964034-B2 Double-structured stick cosmetic and manufacturing method thereof TOKIWA CORPORATION (JP) 2024-04-23 US disclosed
US-20230053578-A1 DOUBLE-STRUCTURED STICK COSMETIC AND MANUFACTURING METHOD THEREOF TOKIWA CORPORATION (JP) 2023-02-23 US disclosed
CN-115702861-A Double-structure stick-shaped cosmetic and manufacturing method thereof 株式会社常盘 2023-02-17 CN disclosed
CN-114344196-A Oily solid cosmetic 株式会社资生堂 2022-04-15 CN disclosed
US-11020327-B2 Gel paste composition and cosmetic using the gel paste composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-01 US disclosed
EP-3072915-B1 GEL PASTE COMPOSITION AND COSMETIC USING THE GEL PASTE COMPOSITION SHINETSU CHEMICAL CO (JP) 2019-09-18 EP disclosed
EP-2431022-B1 Composition based on a cross-linked fluorine-containing silicone for a cosmetic composition SHINETSU CHEMICAL CO (JP) 2017-02-22 EP disclosed
EP-3072915-A1 GEL PASTE COMPOSITION AND COSMETIC USING THE GEL PASTE COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2016-09-28 EP disclosed
US-20160262991-A1 GEL PASTE COMPOSITION AND COSMETIC USING THE GEL PASTE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-15 US disclosed
US-8574557-B2 Composition for a cosmetic and a cosmetic comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-11-05 US disclosed
EP-2431022-A2 Composition based on a cross-linked fluorine-containing silicone for a cosmetic composition Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20110217250-A1 COMPOSITION FOR A COSMETIC AND A COSMETIC COMPRISING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160262991-A1 GEL PASTE COMPOSITION AND COSMETIC USING THE GEL PASTE COMPOSITION COL2A1, HAO2, H1-2 AKT1 3547/4885LDHA 2628/4885EPHX2 29/4885
US-11020327-B2 Gel paste composition and cosmetic using the gel paste composition COL2A1, HAO2, H1-2 AKT1 3547/4885LDHA 2628/4885EPHX2 29/4885
US-20110217250-A1 COMPOSITION FOR A COSMETIC AND A COSMETIC COMPRISING THE SAME FUCA1, F7, F12 AKT1 1544/4885LDHA 2117/4885EPHX2 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.