Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479828 | 0.93 | MAPK9 (0.52) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL4968910 | 0.87 | MAPK9 (0.52) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL3479929 | 0.79 | DRD2 (0.60) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL7893021 | 0.79 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2424858 | 0.79 | MAPK9 (0.61) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2425741 | 0.79 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL6430936 | 0.78 | MAPT (0.45) | KMT2AMEN1MAPTLMNATHRB | |
| SCHEMBL2419914 | 0.78 | HSD11B1 (0.58) | MAPK9MAPK10 | |
| SCHEMBL2425191 | 0.77 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL7894718 | 0.77 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |