Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479828 | 0.82 | MAPK9 (0.52) | MAPTALDH1A1KDM4EKMT2ALMNA | |
| Benzamide SCHEMBL7444468 | 0.78 | MAPK9 (0.50) | MAPTTHRBALDH1A1KMT2ALMNA | |
| SCHEMBL4968910 | 0.73 | MAPK9 (0.52) | MAPTALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL3201898 | 0.73 | MAPT (0.78) | MAPTKDM4EKMT2ALMNAL3MBTL1 | |
| SCHEMBL6022166 | 0.71 | USP5 (0.44) | ALDH1A1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL3216127 | 0.66 | MAPT (0.71) | MAPTALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL7896074 | 0.66 | MAPK9 (0.48) | MAPTTHRBALDH1A1KMT2ALMNA | |
| SCHEMBL6436596 | 0.65 | LMNA (0.40) | ALDH1A1KDM4EKMT2ALMNAL3MBTL1 | |
| SCHEMBL2425191 | 0.65 | MAPK9 (0.51) | MAPTALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7894718 | 0.65 | MAPK9 (0.51) | MAPTALDH1A1KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | disclosed |