Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444519 | 1.00 | POLB (0.52) | POLBATMFKBP1AALDH1A1MMP2 | |
| SCHEMBL995333 | 0.89 | POLB (0.51) | POLBFKBP1AALDH1A1HPGDCHRM2 | |
| SCHEMBL995328 | 0.89 | POLB (0.51) | POLBFKBP1AALDH1A1HPGDCHRM2 | |
| SCHEMBL995331 | 0.89 | POLB (0.51) | POLBFKBP1AALDH1A1HPGDCHRM2 | |
| SCHEMBL23485199 | 0.88 | POLB (0.61) | POLBFKBP1AALDH1A1 | |
| SCHEMBL7433978 | 0.88 | POLB (0.61) | POLBFKBP1AALDH1A1 | |
| SCHEMBL2678864 | 0.88 | POLB (0.61) | POLBFKBP1AALDH1A1 | |
| SCHEMBL30564487 | 0.88 | POLB (0.61) | POLBFKBP1AALDH1A1 | |
| SCHEMBL11264038 | 0.88 | FKBP1A (0.53) | FKBP1AALDH1A1HPGDCHRM2CHRM4 | |
| SCHEMBL16583992 | 0.87 | POLB (0.58) | POLBFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995009859-A1 | BOROPEPTIDE INHIBITORS OF THROMBIN WHICH CONTAIN A SUBSTITUTED PYRROLIDINE RING | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-13 | — | — | WO | disclosed |