Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.42 |
| ▸ | IL6ST | P40189 | 5/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5760623 | 1.00 | CTSS (0.42) | CTSSIL6STSTAT3CTSKIDH1 | |
| SCHEMBL7445465 | 1.00 | CTSS (0.42) | CTSSIL6STSTAT3CTSKIDH1 | |
| SCHEMBL5760620 | 1.00 | CTSS (0.42) | CTSSIL6STSTAT3CTSKIDH1 | |
| SCHEMBL4717588 | 0.91 | CTSS (0.47) | CTSSCTSKCTSL | |
| SCHEMBL7551846 | 0.77 | IL6ST (0.39) | CTSSIL6STSTAT3CTSKIDH1 | |
| SCHEMBL5755859 | 0.76 | CTSS (0.52) | CTSSCTSK | |
| SCHEMBL5755864 | 0.76 | CTSS (0.52) | CTSSCTSK | |
| SCHEMBL7439715 | 0.76 | FKBP1A (0.47) | IL6ST | |
| SCHEMBL7327072 | 0.76 | FKBP1A (0.47) | IL6ST | |
| SCHEMBL7439721 | 0.76 | FKBP1A (0.47) | IL6ST |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780514-A | 2-(4-(4-CHLOROPHENYL)CYCLOHEXYL)-3-HYDROXY-1,4-NAPHTHOQUINONE OR SALT ADMINISTRATION | GLAXO WELCOME INC. (US) | 1998-07-14 | — | — | US | claimed |
| US-5856362-A | PARASITICIDE; 2-(4-(4-CHLOROPHENYL)CYCLOHEXYL-3-HYDROXY-1,4-NAPHTHOQUINONE | GLAXO WELLCOME INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5856362-A | PARASITICIDE; 2-(4-(4-CHLOROPHENYL)CYCLOHEXYL-3-HYDROXY-1,4-NAPHTHOQUINONE | GLAXO WELLCOME INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5780514-A | 2-(4-(4-CHLOROPHENYL)CYCLOHEXYL)-3-HYDROXY-1,4-NAPHTHOQUINONE OR SALT ADMINISTRATION | GLAXO WELCOME INC. (US) | 1998-07-14 | — | — | US | disclosed |
| US-5780514-A | 2-(4-(4-CHLOROPHENYL)CYCLOHEXYL)-3-HYDROXY-1,4-NAPHTHOQUINONE OR SALT ADMINISTRATION | GLAXO WELCOME INC. (US) | 1998-07-14 | — | — | US | disclosed |
| US-5698226-A | CONTAINING LAMOTRIGINE, SWELLABLE CLAY, DISINTEGRATING AGENT WITHIN GRANULES OF TABLET | GLAXO WELLCOME INC. (US) | 1997-12-16 | — | — | US | disclosed |