Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | IL6ST | P40189 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439715 | 1.00 | FKBP1A (0.47) | FKBP1APOLBGAAHPGDALDH1A1 | |
| SCHEMBL7439721 | 1.00 | FKBP1A (0.47) | FKBP1APOLBGAAHPGDALDH1A1 | |
| SCHEMBL9220378 | 0.92 | KMT2A (0.45) | FKBP1APOLBGAAHPGDALDH1A1 | |
| SCHEMBL9220375 | 0.92 | KMT2A (0.45) | FKBP1APOLBGAAHPGDALDH1A1 | |
| SCHEMBL9220381 | 0.92 | KMT2A (0.45) | FKBP1APOLBGAAHPGDALDH1A1 | |
| SCHEMBL9214752 | 0.91 | MAPT (0.47) | FKBP1APOLBGAAMAPTPKM | |
| SCHEMBL3811785 | 0.79 | REN (0.41) | ALDH1A1IL6STMEN1KMT2AKDM4E | |
| SCHEMBL2295984 | 0.79 | REN (0.41) | ALDH1A1IL6STMEN1KMT2AKDM4E | |
| SCHEMBL3811779 | 0.79 | REN (0.41) | ALDH1A1IL6STMEN1KMT2AKDM4E | |
| SCHEMBL7269161 | 0.78 | FKBP1A (0.62) | FKBP1APOLBGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364844-A | Hypotensive agents | SANKYO COMPANY, LIMITED (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0326364-B1 | Renin inhibitory oligopeptides, their preparation and use | SANKYO CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0326364-A2 | Renin inhibitory oligopeptides, their preparation and use | Sankyo Company Limited (JP) | 1989-08-02 | — | — | EP | disclosed |