Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | NCF1 | P14598 | 1/20 | 0.66 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599286 | 0.90 | AKR1C3 (0.58) | AKR1C3SMN1; SMN2TRPV1CYP2C9CYP2C19 | |
| SCHEMBL8838202 | 0.83 | AKR1C3 (0.54) | AKR1C3SMN1; SMN2TRPV1CYP2C9CYP2C19 | |
| SCHEMBL27471218 | 0.83 | ALDH1A1 (0.66) | AKR1C3SMN1; SMN2TRPV1CYP2C9CYP2C19 | |
| SCHEMBL6180189 | 0.81 | ALDH1A1 (0.58) | ADRB2NCF1PLD1SMN1; SMN2CYP2C9 | |
| SCHEMBL894239 | 0.80 | ADRB2 (1.00) | ADRB2NCF1PLD1CYP2C9CYP2C19 | |
| SCHEMBL74335 | 0.80 | ADRB2 (1.00) | ADRB2NCF1PLD1CYP2C9CYP2C19 | |
| Acetic Acid SCHEMBL27482977 | 0.80 | ADRB2 (0.76) | ADRB2NCF1PLD1CYP2C9CYP2C19 | |
| Formaldehyde SCHEMBL28065716 | 0.79 | ADRB2 (0.88) | ADRB2NCF1PLD1CYP2C9CYP2C19 | |
| SCHEMBL6179989 | 0.79 | LSS (0.59) | ADRB2NCF1PLD1ITGB3ITGA2B | |
| SCHEMBL6791781 | 0.79 | ITGB3 (0.57) | ADRB2NCF1PLD1ALDH1A1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440972-B1 | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors | ZENECA LIMITED (GB) | 2002-08-27 | — | — | US | disclosed |
| EP-0966460-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS OXIDO-SQUALENE CYCLASE INHIBITORS | ZENECA LIMITED (GB) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998035956-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS OXIDO-SQUALENE CYCLASE INHIBITORS | ZENECA LIMITED (US) | 1998-08-20 | — | — | WO | disclosed |