Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443348 | 0.84 | KMT2A (0.70) | SMN1; SMN2MEN1KMT2AMAPTRECQL | |
| SCHEMBL23857902 | 0.81 | RAB9A (0.57) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL5145754 | 0.78 | KMT2A (0.62) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL28745974 | 0.78 | GAA (0.79) | SMN1; SMN2HTTKMT2AMAPTRAB9A | |
| SCHEMBL11221078 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL23857904 | 0.78 | FNTA (0.67) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL28069955 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL18922444 | 0.78 | MEN1 (0.60) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL8914692 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL18922446 | 0.77 | HDAC1 (0.72) | SMN1; SMN2HTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364493-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1990-04-25 | — | — | EP | claimed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | claimed |
| EP-0364493-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |