SCHEMBL744481

SCHEMBL744481

COc1c(O)ccc(C(=O)c2ccccc2)c1S(=O)(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.54
LMNA P02545 6/20 0.54
KMT2A Q03164 5/20 0.54
ALDH1A1 P00352 4/20 0.54
HTT P42858 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MAPK1 P28482 3/20 0.51
HPGD P15428 3/20 0.51
CYP1A2 P05177 1/20 0.51
PGR P06401 1/20 0.51
CYP2D6 P10635 1/20 0.51
SLC6A2 P23975 1/20 0.51
PDE4A P27815 1/20 0.51
CYP2C19 P33261 1/20 0.51
HRH1 P35367 1/20 0.51
SLC6A3 Q01959 1/20 0.51
PDE4D Q08499 1/20 0.51
KDM4E B2RXH2 3/20 0.49
HSD17B10 Q99714 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735933 0.86 LMNA (0.50) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL500619 0.86 MAPT (0.56) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL7767220 0.82 MAPT (0.60) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL9619784 0.81 LMNA (0.55) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL25381912 0.80 MAPT (0.64) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL5181784 0.80 KMT2A (0.49) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL28446987 0.79 MAPT (0.36) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL9239540 0.78 LMNA (0.56) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL28797608 0.78 MAPT (0.58) MAPTLMNAKMT2AALDH1A1HTT
SCHEMBL8428909 0.77 KMT2A (0.49) MAPTLMNAKMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118161520-A Lipolytic composition using surface-modified gas-generating nanoparticles 超新星生物有限公司 2024-06-11 CN disclosed
CN-115137664-B Cosmetic composition for improving skin activity containing Astragalus membranaceus peptide maturation matter 株式会社现代百朗德 2024-05-17 CN disclosed
CN-117917963-A Lactobacillus plantarum derived vesicles and uses thereof MD保健株式会社 2024-04-23 CN disclosed
CN-114828834-B Lipolytic composition using surface-modified gas-generating nanoparticles 超新星生物有限公司 2024-03-26 CN disclosed
CN-117500514-A Lactobacillus acidophilus derived vesicles and uses thereof MD保健株式会社 2024-02-02 CN disclosed
CN-117462447-A Cosmetic composition for skin regeneration comprising sucralfate 蔻诗曼嘉韩国股份公司 2024-01-30 CN disclosed
CN-116964154-A Water-dispersible product of silicone rubber particles and cosmetic 信越化学工业株式会社 2023-10-27 CN disclosed
CN-116648264-A Pharmaceutical composition for long-term storage of liquid formulations of botulinum toxin ATGC 股份有限公司 2023-08-25 CN disclosed
US-20230173099-A1 LIPOLYSIS COMPOSITION USING SURFACE-MODIFIED GAS-GENERATING NANOPARTICLES SUPERNOVA BIO CO., LTD. (KR) 2023-06-08 US disclosed
US-11518735-B2 Pseudoceramide compound with improved stability and composition comprising same AE KYUNG INDUSTRIAL CO., LTD. (KR) 2022-12-06 US disclosed
EP-2765145-A1 SILYLATED POLYBUTADIENE Nippon Soda Co., Ltd. (JP) 2014-08-13 EP disclosed
US-20140206789-A1 SILYLATED POLYBUTADIENE NIPPON SODA CO., LTD. (JP) 2014-07-24 US disclosed
US-8574557-B2 Composition for a cosmetic and a cosmetic comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-11-05 US disclosed
US-20120129838-A1 Composition for Preventing and Treating Alopecia Disorder Containing Morgalanthamine Compounds as an Active Ingredient THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (KR) 2012-05-24 US disclosed
EP-2431022-A2 Composition based on a cross-linked fluorine-containing silicone for a cosmetic composition Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20110217250-A1 COMPOSITION FOR A COSMETIC AND A COSMETIC COMPRISING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-09-08 US disclosed
US-7232857-B2 Radiation hardenable adhesive composition containing dispersed natural rubber fine particles TOPPAN FORMS CO., LTD. (JP) 2007-06-19 US disclosed
EP-1398360-B1 RADIATION HARDENABLE ADHESIVE COMPOSITION CONTAINING DISPERSED NATURAL RUBBER FINE PARTICLES TOPPAN FORMS CO LTD (JP) 2006-08-16 EP disclosed
US-20050080181-A1 Radiation hardenable adhesive composition containing dispersed natural rubber fine particles TOPPAN FORMS CO., LTD. (JP) 2005-04-14 US disclosed
EP-1398360-A1 RADIATION HARDENABLE ADHESIVE COMPOSITION CONTAINING DISPERSED NATURAL RUBBER FINE PARTICLES Toppan Forms Co., Ltd (JP) 2004-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120129838-A1 Composition for Preventing and Treating Alopecia Disorder Containing Morgalanthamine Compounds as an Active Ingredient MITF, GLA, GALNT3 MAPT 785/4885LMNA 1602/4885KMT2A 1882/4885
US-11518735-B2 Pseudoceramide compound with improved stability and composition comprising same CERS2, ASAH2, ASAH1 MAPT 1509/4885LMNA 2931/4885KMT2A 2355/4885
US-20110217250-A1 COMPOSITION FOR A COSMETIC AND A COSMETIC COMPRISING THE SAME FUCA1, F7, F12 MAPT 4525/4885LMNA 1333/4885KMT2A 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.