Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179884 | 0.95 | MEN1 (0.66) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL30927046 | 0.95 | MEN1 (0.66) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL7449594 | 0.89 | MEN1 (0.84) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL27179830 | 0.87 | MEN1 (0.69) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL7444940 | 0.86 | MEN1 (0.65) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL30926962 | 0.86 | MEN1 (0.66) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL27181037 | 0.86 | MEN1 (0.66) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL13532166 | 0.85 | MEN1 (0.76) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL30926958 | 0.83 | MEN1 (0.88) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL27181097 | 0.83 | MEN1 (0.88) | MEN1KMT2ALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |