Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450408 | 0.91 | MEN1 (0.62) | MEN1KMT2AHPGDMAPK10MAPT | |
| SCHEMBL7454553 | 0.90 | MEN1 (0.79) | MEN1KMT2AHPGDMAPK10MAPT | |
| SCHEMBL7450127 | 0.88 | MEN1 (0.80) | MEN1KMT2AMAPTPOLB | |
| SCHEMBL7457708 | 0.88 | MEN1 (0.56) | MEN1KMT2AHPGDMAPK10MAPT | |
| SCHEMBL7452610 | 0.87 | CASP3 (0.56) | MEN1KMT2AHPGDMAPK10MAPT | |
| SCHEMBL7445907 | 0.87 | MEN1 (0.65) | MEN1KMT2AHPGDMAPK10ADORA3 | |
| SCHEMBL7604529 | 0.86 | MEN1 (0.66) | MEN1KMT2AMAPTLMNAADORA3 | |
| SCHEMBL27181012 | 0.85 | LMNA (0.62) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7450548 | 0.84 | POLB (0.59) | MEN1KMT2AHPGDMAPK10MAPT | |
| SCHEMBL7444940 | 0.84 | MEN1 (0.65) | MEN1KMT2AMAPTLMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |