Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450844 | 0.85 | SRD5A2 (0.51) | KMT2ASRD5A2FGFR2MAPTTDP1 | |
| SCHEMBL6257064 | 0.81 | SRD5A2 (0.47) | KMT2ASRD5A2FGFR2MAPTTNF | |
| SCHEMBL21749959 | 0.79 | KDM4E (0.53) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL27727269 | 0.77 | ATR (0.51) | ALDH1A1LMNAGAAKMT2ACA1 | |
| SCHEMBL6255305 | 0.76 | MAPT (0.52) | ALDH1A1LMNAF2KMT2AFGFR2 | |
| SCHEMBL28947701 | 0.76 | NAPRT (0.47) | ALDH1A1LMNAGAAKMT2ACA1 | |
| SCHEMBL6257357 | 0.76 | ATR (0.48) | F2KMT2ASRD5A2FGFR2MAPT | |
| SCHEMBL7437658 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAF2KMT2A | |
| Ammonia Solution, Strong SCHEMBL7084475 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAGAASRD5A2CA1 | |
| SCHEMBL6172186 | 0.72 | ALDH1A1 (0.48) | ALDH1A1LMNAGAAF2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |