Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445014 | 0.85 | ALDH1A1 (0.45) | SRD5A2TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6257064 | 0.84 | SRD5A2 (0.47) | SRD5A2TDP1EPHX2NPC1RAB9A | |
| SCHEMBL19857454 | 0.75 | NAPRT (0.57) | TDP1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20520335 | 0.74 | NAPRT (0.47) | TDP1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL6257357 | 0.74 | ATR (0.48) | SRD5A2TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8798744 | 0.72 | NAPRT (0.44) | TDP1RAB9AKMT2ANAPRT | |
| SCHEMBL22750385 | 0.72 | ATR (0.40) | TDP1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL23566361 | 0.72 | GLRA3 (0.43) | RXRARXRBKMT2ANAPRT | |
| SCHEMBL11176158 | 0.72 | TDP1 (0.66) | SRD5A2TDP1NR1H4NPC1RAB9A | |
| SCHEMBL29550462 | 0.72 | TDP1 (0.66) | SRD5A2TDP1NR1H4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |