Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137255 | 0.84 | GRIN1 (0.41) | FFAR1ITGB3ITGA2B | |
| SCHEMBL6942400 | 0.84 | ITGB3 (0.41) | FFAR1ITGB3ITGA2BGRM5 | |
| SCHEMBL6946924 | 0.81 | POLB (0.46) | FFAR1PPARDITGB3ITGA2BALDH1A1 | |
| SCHEMBL7445303 | 0.78 | DRD2 (0.41) | FFAR1PPARDPPARAITGB3ITGA2B | |
| SCHEMBL6951468 | 0.75 | ITGB3 (0.46) | FFAR1PPARDPPARAITGB3ITGA2B | |
| SCHEMBL7445038 | 0.73 | ITGB3 (0.46) | L3MBTL1ITGB3ITGA2BTSHR | |
| SCHEMBL7437608 | 0.68 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL7273518 | 0.67 | ABCB1 (0.46) | FFAR1L3MBTL1PPARDPPARAITGB3 | |
| SCHEMBL7445371 | 0.67 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL7437618 | 0.67 | ITGB3 (0.52) | FFAR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |