Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442500 | 0.83 | TRPA1 (0.34) | CCR1TRPA1MEN1KMT2AKDM4E | |
| SCHEMBL7427062 | 0.81 | SIGMAR1 (0.36) | MEN1KMT2APTGDR2ALDH1A1POLB | |
| SCHEMBL9131964 | 0.78 | ALDH1A1 (0.37) | KDM4EPTGDR2ALDH1A1POLBCCNE1 | |
| SCHEMBL9130879 | 0.76 | ALDH1A1 (0.39) | PTGDR2ALDH1A1POLBMAPTTSHR | |
| SCHEMBL7444364 | 0.70 | MAPT (0.40) | MEN1KMT2APTGDR2ALDH1A1POLB | |
| SCHEMBL9132198 | 0.69 | TRPA1 (0.44) | ACETRPA1KDM4EANPEPPOLB | |
| SCHEMBL9130910 | 0.69 | HCRTR1 (0.35) | PTGDR2ALDH1A1 | |
| SCHEMBL7437251 | 0.67 | MEN1 (0.42) | MEN1KMT2ACCNE1CDK2 | |
| SCHEMBL7437217 | 0.65 | TACR1 (0.39) | — | |
| SCHEMBL7441986 | 0.64 | ALDH1A1 (0.40) | MEN1KMT2APTGDR2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |