Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443255 | 0.87 | CA1 (0.39) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL7445228 | 0.86 | CA1 (0.44) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL10358181 | 0.85 | CA1 (0.42) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9676521 | 0.84 | CA1 (0.46) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9675593 | 0.84 | CA1 (0.46) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL10866353 | 0.83 | REN (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9676607 | 0.83 | REN (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9677769 | 0.83 | REN (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9551920 | 0.83 | REN (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9551921 | 0.83 | REN (0.43) | CA1CA2CA7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364493-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |