Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 19/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | PLD2 | O14939 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | C5 | P01031 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8589966 | 0.99 | ESR1 (0.58) | ESR1ESR2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL7451880 | 0.93 | HRH3 (0.51) | ESR1ESR2ALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL7414836 | 0.92 | ESR1 (0.58) | ESR1ESR2ALDH1A1HSD17B10MAPT | |
| SCHEMBL7817318 | 0.92 | ESR1 (0.48) | ESR1ESR2ALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL7445743 | 0.91 | ESR1 (0.59) | ESR1ESR2ALDH1A1HSD17B10MAPT | |
| SCHEMBL7444427 | 0.86 | ESR1 (0.50) | ESR1ESR2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL7442275 | 0.85 | ESR1 (0.47) | ESR1ESR2ALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL8642388 | 0.82 | ESR1 (0.55) | ESR1ESR2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL7772092 | 0.81 | ESR1 (0.56) | ESR1ESR2ALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL7452427 | 0.79 | ESR1 (0.51) | ESR1ESR2ALDH1A1HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980366-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0980366-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998049160-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |